Omar Sbaih Introduction

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Hi everyone, my name is Omar Sbaih and I am a rising sophomore in the College of Arts of Sciences. I am majoring in neurobiology with a minor in philosophy. This summer, I am thrilled to have the opportunity to engage in research under the guidance of Professor Rhonda Dzakpasu. Our research focuses on investigating the indirect effects of nicotine on neuronal networks through chemical exchange. The project serves both as a demonstration of highly novel equipment and as a preliminary step to future research as we plan to utilize a dual-chambered, partitioned ring attached to an array of microelectrodes (MEA) to observe patterns in neuronal synchronization. This new approach facilitates monitoring of two distinct networks that can communicate via solution exchange offering a new model for chemical propagation within neuronal networks.

Through this research, I aim to deepen my understanding of the effects of nicotine on neuronal networks and contribute to the scientific knowledge surrounding nicotine addiction and its impact on the brain. By elucidating the indirect effects of nicotine, we may be able to uncover potential therapeutic interventions or preventive measures. In addition to its immediate application in studying the effects of nicotine on neuronal networks, the utilization of the dual-chambered MEA opens up exciting new possibilities for future research. By allowing for communication between two distinct networks via solution exchange, this innovative equipment provides a unique model for studying chemical propagation within neuronal networks. The ability to observe and analyze patterns in synchronization between these networks presents opportunities to investigate various aspects of neural communication, such as the effects of other substances or interventions on inter-network signaling and intricate interactions between different brain regions or cell types, providing valuable insights into complex neurological processes. 

Moreover, this summer experience offers me the opportunity to develop my research skills and gain hands-on experience in a laboratory setting. I am excited to work closely with Professor Dzakpasu and the research team, honing my techniques in experimental design, data collection, and analysis. Additionally, I look forward to collaborating with other Laidlaw researchers and engaging in scientific discussions to expand my knowledge beyond the scope of my coursework.

I am so excited for this summer and I look forward to meeting everybody! Please feel free to connect with me and reach out!  

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