I am an incoming Junior double-majoring in Biology and Chinese. My research project for this summer focuses on the galectin-3 binding protein (G3BP). According to the Center for Disease Control, in 2020, over 1.6 million new cancer cases were reported and 600 thousand people died of cancer. While cancer cases are decreasing, for every 100,000 people, there are still 403 new cancer cases.
My research this summer focuses on G3BP, a protein that was identified as an interacting partner for extracellular 6-O-endosulfatase Sulf2. Interaction with G3BP inhibits Sulf2 activity leading to changes of heparan sulfation that is involved in numerous biological processes including cancer cell proliferation, migration and/or invasion. Generation of Gal3BP F357W mutant is recommended by C. Barinka for interaction analyses; we will generate the F357W mutant and test the impact of the mutation on Sulf2-G3BP interactions and the effects on Sulf2 activity.
This research entails the generation of F357W G3BP mutant by site-directed mutagenesis, subcloning wild-type and mutant sequence into lentiviral transfer vector, generation of lentiviral particles in HEK293T cells, transduction of target production cell line, purification by His/Twin-Strep affinity, impact on interaction, impact on enzymatic activity by HPLC-UV-based assay using heparan sulfate mimetic. Through this research, I hope to characterize the interaction between G3BP and Sulf-2 and generate resources (recombinant proteins) for further studies including migration/invasion assays, and utilize the above resources and data.
I am also interested in researching health disparities concerning cancer treatment; unlike other racial groups, cancer is the leading cause of death for Asian Americans. Due to language and cultural barriers, Asian Americans often have lower rates of cancer screening and a lack of proper treatment. Beyond my research in the lab, I am also interested in healthcare access regarding cancer diagnosis and treatment.
Hi! I am a rising third-year in the College of Arts and Sciences majoring in neurobiology and minoring in science, technology, and international affairs. During my research summer, I will be using metagenomics to study the diversity and ecological role of viruses in Antarctic soil microbial communities with the Johnson Biosignatures Lab at Georgetown.
To give some context, metagenomics is a powerful bioinformatics sub-discipline that leverages genetic sequencing and data processing technologies to study microbial communities in their natural environments. Not only does this research allow us to better understand the ecological structure of environmental microbial ecosystems and how they play critical roles in cycling nutrients at a planetary scale, but studying microbial life can help us understand how life evolved on Earth in the first place. As we continue to overshoot planetary boundaries on Earth while simultaneously exploring deeper into outer space, these questions of how does our planetary system really work and what could such a living system look like on other planets become more and more important.
If you're interested in reaching out to talk about biology, any of my "hobbies," your research, or anything else, feel free!!
Hello people!!! I'm Delaney. I am a rising Junior at Georgetown University studying International History in the School of Foreign Service- I am planning to minor in Spanish and Math. My major concentration is Colonial Legacies and Social Structures, intending to promote Decoloniality, the deconstruction of colonial logic and the perceived naturalness of racial capitalism. I graduated from Waconia High School in Minnesota (about 30 minutes west of the Twin Cities).
My research project for this Summer (2024) focuses on Black Resiliency in the British Caribbean, plus how foodways contribute to cultural transmission. With a research team, I traveled to Cat Island in the Bahamas and interviewed local farmers, historians, herbologists, and artisans to collect their primary perspectives and oral histories. Moving forward, I want to synthesize the lingering effects of British occupation on Cat Island, as well as promote the sustainable lifestyle that many Bahamians have inherited through generations.
Hello,
My name is Ema Eguchi and I am an undergraduate student at Georgetown University. I am studying Culture and Politics, with minors in Global Development and Journalism. My research for the Laidlaw Scholars Program is entitled The Role of the Australia Group in US Biosecurity Policy. I am excited to get to know you all and please feel free to let me know if you are also interested in the impact of international NGOs on governments, or broadly, any other topics of international affairs.
I love cooking, hot springs, and beaches!
Hello everyone. My name is Samantha and I am junior in the School of Foreign Service at Georgetown University. I am pursuing a major in International Politics and a minor in Cognitive Science. I am originally from Connecticut. In my free time, I enjoy reading realistic fiction novels and going on walks.
For my research summer, my faculty mentored project was titled African American Resiliency in the British Caribbean and I conducted research under Professor Anita Gonzalez of the American American Studies Department at Georgetown. The project focused on Cat Island, one of the out islands in The Bahamas, and explored the culture of Cat Island by mapping the island’s foodways, music traditions, and histories. Research methods included conducting oral interviews with local residents of Cat Island and participating in cultural practices. Ultimately, the project examined how Bahamian culture reflects the resiliency of Black populations that have survived forced migration and enslavement in the Caribbean.
For my Leadership-in-Action project, I worked at Yahad - in Unum in Paris, France. The nonprofit is dedicated to investigating mass atrocities through interviewing witnesses and examining the sites of mass graves. Currently, Yahad has ongoing investigations in Eastern Europe, Guatemala, Iraq, and Ukraine. Additionally, the organization prioritizes genocide education. My independent project is dedicated to creating a Holocaust education workshop in collaboration with a museum in South Africa.
Colleen Dougherty
Assistant Director, Center for Research & Fellowships, Georgetown University
Colleen manages the Laidlaw Scholars Leadership and Research Programme at Georgetown University. Through her work, Colleen aims to increase accessibility in fellowships advising for all Georgetown students with a special focus on reflective practices intended to help students identify and develop personal and career goals. Prior to joining Georgetown University, Colleen served as the Assistant Director for Early Career Initiatives with NASPA- Student Affairs Administrators in Higher Education, where she managed professional development programs for undergraduate student, graduate student, and new professional members. Colleen holds a master’s degree in Student Development in Higher Education from the University of Maine and bachelor’s degrees in Women and Gender Studies and Anthropology from the University of Delaware.