Hi! My name is Erica Hahn, and I am a rising sophomore at Georgetown University, majoring in Biochemistry. 

This summer, I will be working with Dr. Rodrigo Maillard from the Chemistry Department. The Maillard lab focuses on the mechanisms of regulation and signal transduction of Protein Kinase A (PKA) which is a family of proteins that works to phosphorylate other proteins in complex signaling pathways in cells. Because PKA is involved in many critical signaling pathways, it has been associated with many diseases including Carney Complex and Acrodysostosis, making it an important therapeutic drug target. My project over this summer would be to observe and detect the behavioral changes of PKA using FRET (fluorescence resonance energy transfer) sensor that our lab developed. Specifically, I will  be observing the interaction between the catalytic subunit of PKA and smoothened protein in hedgehog signaling which has shown to regulate PKA activity, different from the traditional PKA regulator cAMP and regulatory subunit. This research will be conducted in collaboration with Dr. Ben Myers from the University of Utah. 

I am very excited to pursue this research opportunities and to connect with various scholars. Please do not hesitate to reach out!