Report Biomedical Sciences Engineering Medical Sciences
Medicine & Health, STEM, Tufts University, Leadership & Research Laidlaw Scholars

Modeling Bulbar-onset ALS using iPSC-derived Motor Neurons

I am honored to share the final product of my research summer, which I spent working with Dr. Nisha Iyer to model bulbar-onset ALS, a particularly aggressive and relatively understudied subtype of ALS.
Go to the profile of Lauren Stoller
Lauren Stoller
Laidlaw Scholar, Tufts University
Like

Share this post

Choose a social network to share with, or copy the URL to share elsewhere

Share with...

This is a representation of how your post may appear on social media. The actual post will vary between social networks

Preview

Open

I spent my Summer 1 in the Iyer Stem Cell and Regeneration Lab at Tufts, working on a disease modeling project targeting bulbar-onset ALS, a subtype of ALS known for its aggressive nature and profound effect on disease prognosis. I cultured stem cell-derived motor neurons specific to the hindbrain region with two known ALS-associated genotypes and analyzed their development, electrophysiological properties, and decline over time compared to healthy neurons, searching for cellular-level signatures contributing to neuron death and disease pathology.

Go to the profile of Lauren Stoller
Lauren Stoller (She/Her)
Laidlaw Scholar, Tufts University

Hi everyone! My name is Lauren, I am a rising junior at Tufts University studying Biomedical Engineering and Science, Technology, & Society. I am very interested in neuroscience research, especially neurodegenerative diseases. I am also very interested in learning about the neuroscience of addiction, and how medical research can be used for social good. In my free time, I enjoy reading, live music, and spending time with loved ones!

Cookie Settings

We and selected partners, use cookies or similar technologies as specified in the cookie policy and privacy policy.

You can consent to the use of such technologies by closing this notice.

Cookie Control

Customise your preferences for any tracking technology

The following allows you to customize your consent preferences for any tracking technology used to help us achieve the features and activities described below. To learn more about how these trackers help us and how they work, refer to the cookie policy. You may review and change your preferences at any time.

Cookie policy Privacy policy
Always active, cannot be turned off
More information

These trackers are used for activities that are strictly necessary to operate or deliver the service you requested from us and, therefore, do not require you to consent.

More information

These trackers help us to deliver personalized marketing content and to operate, serve and track ads.

More information

These trackers help us to deliver personalized marketing content to you based on your behaviour and to operate, serve and track social advertising.

More information

These trackers help us to measure traffic and analyze your behaviour with the goal of improving our service.

More information

These trackers help us to provide a personalized user experience by improving the quality of your preference management options, and by enabling the interaction with external networks and platforms.