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From Bench to Bedside: The Development & Evaluation of Orodispersible Films for Paediatric Drug Delivery
I explored the development of Orodispersible Films through laboratory research at the UCL School of Pharmacy and its evaluation as a child-friendly, palatable formulation at Great Ormond Street Hospital to manage the treatment of chemotherapy-induced nausea and vomiting in paediatric oncology.
Overall, this project supports the continued development and clinical evaluation of ODFs as a means of improving medication adherence, comfort, and therapeutic outcomes in children undergoing chemotherapy and experiencing CINV.
Ravleen Kaur Gujral
(She/Her)
Student Pharmacist, UCL
Hello! :) I'm Ravleen, a 2nd year Pharmacy student at UCL.
In the last year, I was introduced to pharmaceutics: a scientific basis for the formulation and manufacture of safe and effective medicines.
Even the most effective medicine doesn't work if the patient refuses to take it. A study found that 79% of children stated that the taste of medicine made them unwilling to take it. Moreover, children are commonly unable to swallow neutral tasting pills, which makes dosing them a challenge.
For my research project, I explored the development of child-friendly, palatable formulations called orodispersible films using a method called electrospinning. This involved hands-on laboratory work to develop prototype formulations at the UCL School of Pharmacy and interviews with paediatric, oncology patients at Great Ormand Street Hospital to improve the treatment of chemotherapy-induced nausea & vomiting.
Feel free to reach out!
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